New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...

Moreover a protein is often separately expressed and modified in order to perform 3D structure analysis ... Initial images have already shown that antibody structures change over time during ...

These chains are held together by disulfide bonds and non-covalent interactions. The structure of an antibody can be divided into several key regions: Variable Regions (Fab): Located at the tips of ...

Immunotherapies use antibodies—proteins that bind to cell ... to predict how proteins fold and interact, developing a 3D ...

Computational design completed in approximately one week with low computational cost • Virtual screening of billions of candidates without relying on antigen and antibody 3D structure • Only ...

"We are finding the 3D structure of the genome," said Satoshi Namekawa, professor of microbiology and molecular genetics at the University of California, Davis and senior author on one of the papers.

Here, we discuss strategies to select the best therapeutic antigen targets, to optimize the structure of IgG antibodies and to design related or new structures with additional functions.