For example, nimesulide is a weak competitive inhibitor of COX-1 but a potent time-dependent inhibitor of COX-2, whereas celecoxib exhibits slow competitive binding and, at higher concentrations ...

Cox-2 inhibitors are a newer form of prescription NSAID. As you might guess, they only affect Cox-2 enzymes and not Cox-1. Two of them -- Bextra and Vioxx -- are no longer sold because of concerns ...

A drug developer's dream, rationally designed to quell inflammation, COX-2 inhibitors are also prime candidates for ... acute pain, and dysmenorrhea.1 But the use for cancer--begun with the 1999 ...

Ibuprofen relieves aches and inflammation that can put a halt to your day. Most people will take ibuprofen every once in a while, but sometimes you might need to take it several times a day after ...

"Very lame and imperfect theories are sufficient to suggest useful experiments which serve to correct those theories and give birth to others more perfect. These, then occasion farther experiments ...