"COX-2 is an ideal target," he says. The COX-2 inhibitors shot to pharmaceutical fame in December 1998, when the Food and Drug Administration approved Celebrex (celecoxib) to treat osteoarthritis and ...

Use of the inflammatory mediators interferon or interleukin-2 to treat cancer or multiple ... the antidepressive effect of the COX2 inhibitor celecoxib in combination with the noradrenergic ...

Both are types of NSAIDs, but they work differently. Celebrex is a selective COX-2 inhibitor that targets inflammation with ...

To protect your stomach, you could consider a COX-2 inhibitor like Celebrex because it blocks inflammation while keeping intact the prostaglandins that protect your stomach and intestines.

The league table listing the 'top 20' drugs includes rofecoxib (Vioxx) and celecoxib (Celebrex), two inhibitors of the prostaglandin-forming cyclooxygenase (COX) (Fig. 1), which between them ...

Debate over the University of Rochester's (UR) claim for royalties from arthritis blockbuster Celebrex continues as UR appeals an early defeat for its patent on cox-2 inhibitors. Though the district ...

The effects of aspirin, nonspecific nonsteroidal anti-inflammatory drugs (NSAIDs), and cyclooxygenase (COX)-2 specific inhibitors on ... Effect of celecoxib and nonspecific nonsteroidal anti ...

All NSAIDs variably inhibit COX-1 and COX-2 and the mechanisms of inhibition fall into three broad categories, although there are exceptions. For example, nimesulide is a weak competitive ...

Selective inhibitors of COX-2 such as Vioxx, Bextra and Celebrex carry an increased risk of heart attack and stroke; there has been in-depth study on comprehending the reasons for this occurrence.