Meloxicam is an enolcarboxamide with preferential COX-2 inhibitory activity. In vitro studies with human tissues have confirmed the high affinity of meloxicam for COX-2, whereas COX-1 was ...

Ferroptosis plays an essential role in chronic liver diseases, and cyclooxygenase-2 (COX-2) affects liver fibrosis through multiple mechanisms. + ...

A drug developer's dream, rationally designed to quell inflammation, COX-2 inhibitors are also prime candidates for preventing cancer or its recurrence. Gary J. Kelloff, chief of the chemoprevention ...

There may be other forms of COX that could account for some of the ... being carboxylic acids (Fig. 2). The main question, from the pharmacologist's point of view, was how these apparently ...

This effect is modified by a genetic variation in cyclo-oxygenase-2 (COX-2), a key enzyme in fatty acid metabolism and inflammation, Fradet et al. report. Previous research has shown that omega-3 ...

Meloxicam is an enolcarboxamide with preferential COX-2 activity. Studies conducted on experimental models and human tissues indicate that meloxicam is a more potent inhibitor of COX-2 than COX-1 ...