A drug developer's dream, rationally designed to quell inflammation, COX-2 inhibitors are also prime candidates for preventing cancer or its recurrence. Gary J. Kelloff, chief of the chemoprevention ...

nimesulide is a weak competitive inhibitor of COX-1 but a potent time-dependent inhibitor of COX-2, whereas celecoxib exhibits slow competitive binding and, at higher concentrations, binds ...

To protect your stomach, you could consider a COX-2 inhibitor like Celebrex because it blocks inflammation while keeping intact the prostaglandins that protect your stomach and intestines.

Targeted preconception counseling and a treat-to-target approach help optimize pregnancy outcomes in women with rheumatoid arthritis, according to a new review.

selective COX-2 inhibitor, and 5-HT1B/1D agonist indicated for the acute treatment of migraine with or without aura. It is also developing AXS-05 (dextromethorphan-bupropion), an investigational N ...

Aspirin and COX-1 inhibitors boost immunity against cancer metastasis, revealing a new pathway for anti-metastatic therapies.

"Very lame and imperfect theories are sufficient to suggest useful experiments which serve to correct those theories and give birth to others more perfect. These, then occasion farther experiments ...