Ferroptosis plays an essential role in chronic liver diseases, and cyclooxygenase-2 (COX-2) affects liver fibrosis through multiple mechanisms. + ...

Purpose: A summary of the basic science underlying the current controversies regarding cyclooxygenase-2 (COX-2)-selective nonsteroidal antiinflammatory drugs (NSAIDs), including data on their ...

COX-2 was cloned in 1991 ... COX is a heme-containing bifunctional protein that sequentially catalyzes two reactions, a COX and a peroxidase reaction. The presence of an endogenous oxidant ...