The process of transcription elongation by RNA polymerase II (Pol II), in which Pol II travels along DNA and synthesizes RNA from DNA, is essential for proper gene expression in all eukaryotic cells.

Novel technology enables discovery, which could help predict tumour recurrence Researchers from the Fred Hutch Cancer Centre, ...

RNA polymerase II phosphorylation regulates a switch between transcriptional ... Architecture of the human and yeast general transcription and DNA repair factor TFIIH. Mol Cell 2015, 59: 794 – 806.

Invitrogen™ Platinum™ SuperFi II DNA Polymerase is a hot-start, engineered proofreading DNA polymerase, providing superior fidelity and specificity to your PCR. With >300x Taq fidelity and buffer ...

Biology lectures teach students that when a cell’s replication machinery comes together, DNA polymerase takes off down the double-helix like a car on a highway ...

A new method for mapping torsion provides insights into the ways that the genome responds to the torsion generated by RNA polymerase II.

Thus, it is RNA pol II that transcribes the messenger ... Once transcription is initiated, the DNA double helix unwinds and RNA polymerase reads the template strand, adding nucleotides to the ...

A new structural blueprint paves the way for improved targeting of cancer cells, particularly those with BRCA1 and BRCA2 ...

Enzymes called RNA polymerases transcribe DNA into RNA. RNA is the intermediary that carries ... of RNA polymerases that can transcribe different types of RNA. RNA polymerase II, shown here, is ...

DNA repair proteins act like the body's editors ... understand how cancer cells hijack one of these proteins -- called polymerase theta (Pol-theta) -- for their own survival.

This polymerase contains four catalytic subunits ... For example, researchers know that RNA pol II can bind to a DNA sequence within the promoter of many genes, known as the TATA box, to initiate ...