T helper 17 (Th17) cells generate the pro-inflammatory cytokine interleukin-17 (IL17/IL17A). IL17 has been a target for a variety of therapeutic monoclonal antibodies and inhibitors to treat ...

Cite this: Functional Interleukin-17 Receptor A is Expressed in Central Nervous System Glia and Upregulated in Experimental Autoimmune Encephalomyelitis - Medscape - Apr 01, 2009. 1 Department of ...

The interleukin-17 (IL-17) family cytokines are strong inducers of inflammation and help to protect us against invading pathogens. However, they also have a dark side and contribute to the tissue ...

Japanese researchers now demonstrate for the first time that the interleukin (IL)-23–IL-17 axis is essential for brain inflammation after stroke. “Macrophages infiltrating the site produce IL ...

This triggers the production of an antiviral molecule, interleukin-17, which strengthens the defenses of the nose and upper respiratory tract. Interleukin-17 plays a key role in protecting against ...

D epartment of Medicine, University of Toronto, Women's College Hospital, and co-authors have found biologics targeting interleukin (IL)-12, IL-23, or IL-17 were associated with a lower rate of ...

A RECENT study has highlighted key biological and clinical factors linked to resistance to biologic therapies in patients ...

Biologics targeting interleukin (IL)-12, IL-23, or IL-17 are linked to a 35% lower rate of serious infections in older adults with psoriatic disease compared to other treatments.