“The LC neurons exhibit signatures suggesting that they are super cholesterol-hungry – these neurons are doing both their best to produce their own cholesterol and take in as much as possible. The SN, ...

Cholesterol regulation and neuronal vulnerability: The study found that neurons in the locus coeruleus (LC)—a brain region highly vulnerable to Alzheimer’s—are extremely dependent on ...

The locus coeruleus (LC) is a small region of the brainstem that produces norepinephrine, a chemical with powerful effects on arousal and wakefulness which plays an important role in the body's ...

"The LC neurons exhibit signatures suggesting that they are super cholesterol-hungry—these neurons are doing both their best to produce their own cholesterol and take in as much as possible.

For these reasons, we turned to mice where the LC consists of only about 3,000 neurons, but these neurons can still exert a significant influence over the 75 million neurons that make up the mouse ...

“The LC neurons exhibit signatures suggesting that they are super cholesterol-hungry – these neurons are doing both their best to produce their own cholesterol and take in as much as possible. The SN, ...