T cells may be broadly classified as either helper T cells (Th cells, CD4+) or cytotoxic T cells (Tc cells, CD8+). In 1986, T.R. Mosmann, R.L. Coffman, and colleagues observed that individual clones ...

The human body usually has a strong defense against viral infections, primarily through the rapid production of anti-viral T cells. Specifically, when a virus is detected, T Helper 1 (Th1 ...

Patients with chronic lymphocytic leukemia (CLL) who experience Richter transformation have a poor prognosis, but ibrutinib ...

Broadly speaking, Th2 cells respond to threats including environmental allergens and parasites, whereas Th1 cells respond to viruses and bacteria. A newborn’s immune system has more Th2 than Th1 ...

Tec family tyrosine kinase specific to Th1 cells; vWF: von Willebrand factor. The lack of longitudinal, prospective study design limits the usefulness of many study results. The heterogeneity and ...

A new review was published as the cover paper of Aging, titled "Types of cell death and their relations to host immunological pathways." Various immune pathways in the host, such as TH1 ...

VD inhibits antigen presentation. VD skews the balance of Th1/Th2 cells toward the latter ones. VD inhibits of Th1 cell differentiation and the production of Th1-specific cytokines. VD facilitates ...