Vincent Gaynor remembers, almost to the minute, when he realized his part in birthing the breakthrough gene therapy Zolgensma ...

Sky star Angel Reese had 22 points and 21 rebounds to lead the Rose to a 72-63 win over the Lunar Owls on Friday in Miami, ...

A naturally occurring ice sculpture formed to mirror the Chicago skyline along the shore of Lake Michigan, stunning footage ...

“Da King of da Monsters has come to da Windy City!” a shocked CTA train operator gulps in “Godzilla vs. Chicago,” the first ...

From quaint neighborhoods and scenic riverwalks to stunning skyline views, Chicago isn’t just bold—it’s cute too! Whether ...

Thanks to new social media efforts Tim Gillengerten's gift shop — with locations in Wicker Park and Andersonville — surpassed ...

Bill Maher accuses Nike of sending a lying message in its Super Bowl ad with Caitlin Clark The Sky are bidding to improve on a .325 record from last time out and to make a push for the playoffs as ...

Some Chicago aldermen are renewing efforts to reinstall statues, including monuments of Christopher Columbus, that were ...

A look inside 2025 Chicago Cubs spring training at Sloan Park in Mesa, Ariz. Get more news from Cubs camp here — and sign up for our Cubs Insider newsletter here. Chicago Cubs outfielder Pete ...

CHICAGO — The Second City was among those with citizens gathering for Presidents Day protests against President Donald Trump and billionaire advisor Elon Musk. Dozens gathered at Federal Plaza ...

More than 1.7 million people make their way to Willis Tower's Skydeck Chicago each year, and it's easy to see why. Occupying the 103rd floor – that's nine floors higher than 360 CHICAGO – of ...