Dach1 follows a broad-to-restricted expression pattern during DRG neuron development. Dach1 expression is progressively restricted mainly to TrkB + LTMR neurons and is required for the sense of touch.

Moreover, researchers found that PNS microglia directly enwrap neuronal somas in peripheral ganglia, forming a Neuron-PNS Microglia-Satellite Glial Cell trio model. This revises the traditional Neuron ...

Diabetic neuropathic pain (DNP) is one of the most prevalent complications of diabetes, characterized by a high global prevalence and a substantial affected population with limited effective ...

The Proclaim DRG neurostimulation device. [Image courtesy of Abbott] Abbott (NYSE: ABT) + announced today that it launched a next-generation delivery system for its neuromodulation business.

Only a modest number of genes switched on or off, far fewer than expected from earlier studies on other neuron types, like sensory neurons in the dorsal root ganglia (DRG). However, when the team ...

We evaluated the effects of chronic hyperglycemia on L5 dorsal root ganglion (DRG) neurons using immunohistochemical and electrophysiologic techniques for evidence of oxidative injury ...

2012). Na V 1.7 is expressed in all types of dorsal root ganglion (DRG) neurons, sympathetic neurons, Schwann cells, and neuroendocrine cells (Catterall et al., 2005). It is responsible for the ...