One notable missing feature in most ANN models is top-down feedback, i.e. projections from higher-order layers to lower-order layers in the network. Top-down feedback is ubiquitous in the brain, and ...

Microscopic image, section of an electroporated, genetically modified chimpanzee brain organoid. Cell nuclei in blue, progenitor cells in magenta, electroporated, genetically modified cells in green ...

More information: Nesil Eşiyok et al, A dyad of human-specific NBPF14 and NOTCH2NLB orchestrates cortical progenitor abundance crucial for human neocortex expansion, Science Advances (2025). Provided ...

According to three Stanford scientists, lack of human biological material is a “major bottleneck to progress” for medical research. A steadily growing idea is one known as “bodyoids ...

In the course of evolution, this interplay has led to the human brain being unique in its size and complexity. The newly gained insights not only provide a deeper understanding of the evolutionary ...

Human “bodyoids” could reduce animal testing, improve drug development, and alleviate organ shortages. Why do we hear about medical breakthroughs in mice, but rarely see them translate into ...

For instance, although the enormous brain of an elephant contains three times as many neurons as the human brain, these are predominantly located in the cerebellum, not in the neocortex that is ...

However, new research has not only challenged this view, it has simultaneously spawned a new mystery surrounding human evolution. Using full genome sequencing, researchers discovered that modern ...

What's more, according to their analysis of modern human DNA, one of these isolated populations left a stronger legacy in our genes than the other. "The question of where we come from is one that has ...

These birds have neurons that are activated when they produce specific vocalizations, similar to how neurons are activated in humans, though in a different region ...